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Short Notes on Breast Cancer 2017 - Dr Mark Burgin

18/05/17.Dr. Mark Burgin BM BCh (oxon) MRCGP considers the elements that should be included in a primer for clinical negligence cases involving breast cancer.

Breast cancer is usually metastatic by the time of diagnosis (1) so that the treatment will involve surgery, chemotherapy and radiotherapy and presently results in a 50% survival at ten years.

More recently the use of new treatments that target the cancer has led to patients choosing to forego the chemotherapy and rely on surgery and drugs like Herceptin or Tamoxifen.

There are two common variants of breast cancer as far as treatment is concerned, first HER2 cancer which used to have a bad prognosis until Herceptin become available in 1998.

The second type is oestrogen receptor positive cancer which is controlled by blocking oestrogen by drugs and chemotherapy.

Research is looking at how variants of these types of cancers identified by gene expression profiling assay behave and potentially...

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